Description
TB-500 10mg Details
TB-500 is a synthetic peptide derived from thymosin β4 (Tβ4), a naturally occurring, highly abundant member of the β-thymosin family first isolated from calf thymus tissue in the 1960s. The peptide is best known in research for its central actin-binding domain — a region structurally complementary to actin, one of the most common structural proteins in biology — which underlies its study as a regulator of G-actin sequestration and cytoskeletal dynamics.
In published research, TB-500 / thymosin β4 has been investigated in cell and animal models for roles in cell migration, angiogenesis and tissue-repair signalling. The peptide adopts a largely unstructured, flexible conformation in solution, which is thought to support its interaction with actin. These findings derive from laboratory and preclinical studies and do not establish any effect in humans.
This product is intended solely as a reference material for in vitro and laboratory research conducted by qualified professionals.
Note on TB-500 forms: The name “TB-500” is used in the research market for two distinct materials — the full-length 43-amino-acid thymosin β4 peptide, and the shorter N-acetylated active fragment Ac-LKKTETQ (residues 17–23). The specifications below reflect the full-length thymosin β4 form most commonly supplied as “TB-500.” Confirm which form your batch contains and match the listed CAS, formula and molecular weight to your lot-specific Certificate of Analysis before publishing.
Specifications
| Property | Detail |
|---|---|
| Product name | TB-500 (Thymosin β4) |
| Quantity | 10mg |
| CAS number | 77591-33-4 (full-length Tβ4) — see fragment alternative below |
| Molecular formula | C₂₁₂H₃₅₀N₅₆O₇₈S |
| Molecular weight | 4963.4 g/mol |
| Chain length | 43 amino acids |
| Synonyms | Thymosin beta-4, Tβ4 |
| Appearance | White to off-white lyophilised powder |
| Purity | ≥98% (HPLC); identity confirmed by mass spectrometry |
| Source | Synthetic |
| Documentation | Lot-specific Certificate of Analysis (COA) |
Alternative form (if your batch is the fragment)
| Property | Detail |
|---|---|
| Identity | Ac-LKKTETQ (N-acetylated fragment, residues 17–23) |
| CAS number | 885340-08-9 |
| Molecular formula | C₃₉H₆₇N₉O₁₃ |
| Molecular weight | 877.99 g/mol |
| Chain length | 7 amino acids (heptapeptide) |
Storage & Handling
Store the lyophilised peptide frozen at -20°C, protected from light and moisture. Once reconstituted with bacteriostatic water, store at 2–8°C and use within a short period; for longer storage, aliquot and freeze to avoid repeated freeze–thaw cycles.
Important Notice
This product is sold strictly for laboratory research purposes only. It is not a medicine, dietary supplement, or cosmetic, and is not intended for human or animal consumption, diagnostic, or therapeutic use. By purchasing, the customer confirms they are a qualified researcher or institution and accept full responsibility for safe and lawful handling. Keep out of reach of children.
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